colgate pro relief vs instant relief

Toothpaste doesn't only clean your teeth; we have products to help with a variety of tooth issues like sensitivity and more. We discuss how this innovative technology works to provide patients with rapid and long-lasting relief from dentin hypersensitivity. Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste delivers instant* and long-lasting sensitivity relief plus gum protection. 2018;9(3):3306. The dropouts of the participants at each efficacy interval may be considered the weakness of this trial that was due to COVID-19 lockdown. We found more change in pain scores of VAS used for mechanical stimuli with Pro-argin than FCPS as shown in Table 5 that could be relatable with a randomised controlled trial of FCPS and arginine based desensitizers reporting better treatment response of arginine than FCPS in the cold stimulated DH after two weeks to one month, subsequently [40]. All rights reserved. volume21, Articlenumber:498 (2021) YYYY Colgate-Palmolive Company. This site is intended for healthcare professionals only. The effect of the incorporation of fluoride into strontium containing bioactive glasses. Colgate Sensitive Pro Relief offers a solution that is clinically proven to relieve sensitivity pain. The study's primary objective was to investigate pain relief in one minute with Pro-argin and strontium acetate in DH measured on SCASS as a primary outcome measure and VAS as a secondary outcome measure. A total of 140 participants were initially enrolled and randomised into the four treatment arms, with thirty-five in each group. Clinically proven lasting relief for 8 weeks. YES Somewhat No WHAT IS THE FLUORIDE CONTENT OF Colgate SENSITIVE INSTANT Relief Repair & Prevent TOOTHPASTE? Hines D: Poster #0742 March 2018 AADR. 2015;42(2):13141. Hu ML, Zheng G, Lin H, Yang M, Zhang YD, Han JM. 1. Moreover, there was no significant difference between dentifrices containing FCPS, Pro-argin, and 8% strontium acetate (p>0.05) on completion of trial after six weeks. [18] in a meta-analysis in 2020. Post-hoc analysis revealed a significant reduction in DH scores in treatment arms compared to control on completing the six-week trial (p<0.05). * *With continued use twice a day Prevents sensitivity from coming back* *With continued use twice a day can help prevent sensitivity from coming back. Colgate Sensitive Instant* Relief Enamel Repair Toothpaste gives you clinically proven lasting relief** from sensitivity for 8 weeks when you use it twice a day. With regular use, it creates a long-lasting protective barrier that acts as a seal against sensitivity. Thank you for your feedback. For instant relief, just apply directly to the sensitive tooth with finger tip and gently massage for one minute. Another meta-analysis by Hu et al. COLGATE. Gentle whitening formula. Provides 24/7 sensitivity protection. Follow the directions for use. Colgate Sensitive Pro-Relief Enamel Repair contains Pro-Argin formula, helping to remineralise enamel, strengthen teeth against acid in food and drinks, plus instantly plugs channels to sensitive nerves. A 3-day randomised clinical study investigating the efficacy of two toothpastes, designed to occlude dentine tubules, for the treatment of dentine hypersensitivity. Colgate Sensitive Pro-Relief Enamel Rebuild also: Fights cavities Strengthens enamel Freshens breath Vegan . Pro-Argin technology can be found in Colgate Sensitive Pro Relief Toothpaste, sold as Colgate Sensitive Instant Relief in the UK and elmex Sensitive Professional in Europe. Product Information. The makers of Colgate Sensitive Pro-Relief and its rival, Sensodyne Rapid Relief, have been dobbing each other into the health regulator over advertising claims that the toothpastes give users "instant" relief to pain from sensitive teeth. Two double-blind randomized clinical studies by Nathoo et al. If symptoms persist, talk to your healthcare professional. Ingredients *Calcium carbonate *Water Colgate Sensitive Pro-Relief It works by plugging the channels to block tooth sensitivity and with regular use. A randomised, controlled, triple-blinded clinical trial was conducted with 140 participants clinically diagnosed with DH and equally randomized into four groups with parallel treatment assignment of FCPS, Pro-Argin, 8% strontium acetate, and sodium fluoride-based OTC dentifrices, and tested for DH with air blast, mechanical, and water jet stimuli on SCHIFF cold air sensitivity scale (SCASS) and visual analogue scale (VAS) at interim efficacy intervals of one minute, three days, two, four, and six weeks, subsequently. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Douglas-de-Oliveira DW, Vitor GP, Silveira JO, Martins CC, Costa FO, Cota LOM. Blocks the pain of sensitive teeth. 1). 2020;99(5):51422. California Privacy Statement, The strength of this study was that participants were randomised into four treatment groups to generalise the results for the population [32]. Directions *For instant relief, apply directly to the sensitive tooth with fingertip, and massage gently for 60 seconds, one a week or less frequently **For lasting relief, apply to a gentle toothbrush making sure to brush all sensitive areas of the teeth. Docimo R, Montesani L, Maturo P, Costacurta M, Bartolino M, DeVizio W, Zhang YP, Cummins D, Dibart S, Mateo LR: Comparing the Efficacy in Reducing Dentine Hypersensitivity of a New Toothpaste Containing 8.0% Arginine, Calcium Carbonate, and 1450 ppm Fluoride to a Commercial Sensitive Toothpaste Containing 2% Potassium Ion: An Eight-Week Clinical Study in Rome, Italy. Treatment difference between FCPS, Pro-argin, and 8% strontium acetate was not statistically significant with a p>0.05 for sustained pain relief in DH. It improves gum health and helps reduce factors that contribute to gum recession, a leading cause of tooth sensitivity. The sensitive toothpaste remineralises tooth enamel for more resistance against acid attacks. Though all bioactive agents have a significant treatment effect in reducing DH, there is currently no consensus on the unequivocal efficacy of any product or bioactive agent used for managing the condition due to huge variations and heterogeneity in the conduct of clinical trials on DH [6]. Aust Dent J. Exclusive Pro-Argin formula. Pro-Argin Technology works through a natural process of dentin tubule occlusion that attracts arginine and calcium carbonate to the dentin surface to form a protective seal that provides instant relief.2 Besides, these findings of the current study could be related to previously conducted clinical trials indicating the better clinical effectiveness of Pro-argin than strontium acetate against air-blast and tactile stimulus after three days and one week of application [30, 31]. Am J Dent. Identifier NCT 04249336. A randomised clinical trial on the efficacy of 5% fluorocalcium phosphosilicate-containing novel bioactive glass toothpaste. The findings agreed with another in vitro trial by Mahmoodi et al. The outcomes are in concordance with the previous studies conducted by Layer and Hughes [26], Zang and Shaw [27], and Mason et al. PubMedGoogle Scholar. 2013;41:S317. Based on the synthesis of study results, we can conclude that Pro-argin in Colgate Sensitive Pro-relief and 8% strontium acetate in Sensodyne Rapid Action both are effective for pain relief in one minute after application in DH with better immediate treatment response of Pro-argin than strontium acetate. Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste is an everyday toothpaste. WAF has contributed to revising the manuscript critically and contributed to statistical analyses. In contrast, there was a significant (p<0.001) reduction of 61.1% with FCPS, 60.1% with Pro-argin, 53.4% with 8% strontium acetate, and 25% with NaF-based dentifrices relative to baseline after subsequent six weeks of application observing sustained relief from DH on SCASS. In our study, Pro-argin treatment revealed an immediate clinical reduction of 45.7% on SCASS, 56% on VAS used for mechanical stimuli, and 48.1% on VAS used for water jet stimuli in DH demonstrated in Tables 3, 5, and 6. 3rd edition, Public Health England 2014. The statistically significant change in mean scores of DH was observed with FCPS with p<0.05 relative to baseline for sustained relief from DH at follow-ups on day 3, week 2, week 4, and week 6, using clinical parameters of SCASS and VAS. Colgate Sensitive Pro-Relief Multi Protection Toothpaste provides clinically proven instant and lasting relief for sensitive teeth For instant relief, apply directly to each sensitive tooth with finger tip and gently massage for 1 minute, up to twice daily *with direct application and daily brushing. 1997;24(11):80813. Many patients tolerate the pain of sensitive teeth because theyre unaware of simple but highly effective answers like Pro-Argin technology. Another . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. Ingredients *Calcium carbonate *Water 2019;46(12):11216. Cite this article. Last updated on May 11, 2021. https://clinicaltrials.gov/ct2/show/NCT04249336. Martins CC, Firmino RT, Riva JJ, Ge L, Carrasco-Labra A, Brignardello-Petersen R, et al. (US). Lavender SA, Petrou I, Heu R, Stranick MA, Cummins D, Kilpatrick-Liverman L, et al. Colgate Sensitive Plus Toothpaste developed for sensitive teeth provides sensitivity protection And helps in Enamel Repair, Cavity . For lsting relief, apply to a gentle toothbrush making sure to brush all sensitive areas of the teeth twice daily. IRB-1351/DUHS/Approval/2019/184. Oral dentifrices have been marketed for pain relief within a minute for DH. Pro-Argin Technology with arginine and an insoluble calcium compound, zinc and 1450ppm fluoride. [16] in a systematic review in 2015. These measures facilitated behaviour modification together with the promotion of knowledge and understanding in the society about DH. TVC Category: Colgate Tooth Paste Benefits Clinically proven sensitivity relief. Thus, 128 participants completed the trial and were statistically analyzed for primary outcome measure of SCASS scores after lost to follow up (Fig. Dentin hypersensitivity treatments work in one of two ways. With its unique Pro-Argin technology, this sensitive toothpaste will give you instant* relief from sensitivity as it helps to seal and repair the sensitive areas of your teeth. Directions 2020;12(2):87. Dent Health Curr Res. Clinical Efficacy Of BioMin F, Colgate Sensitive Pro-Relief And Sensodyne Rapid Action Dentifrices In DH The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. In our study, patient compliance related to the recommended time of application and method of the application provided by doctors was controlled by subjecting multiple efficacy intervals and different methods for assessment of the change in pain scores due to DH. Table 6 presents the change in the mean scores on VAS against waterjet stimulus from baseline to subsequent efficacy interval within each treatment arm. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. OTC dentifrices were applied and massaged gently with the applicator on at least two sensitive teeth per subject at two different sites, including cementoenamel junction and exposed dentinal surface, by the doctor in the office during the first visit. In addition, they should be reproducible and clinically relevant to stimuli triggering pain in DH [35]. All the treatment groups showed statistically significant improvement in DH with p<0.001 relative to baseline at all time points. Size: 75ml (Approx.) Help Caregivers Understand Caries | Colgate Professional, compared to a leading brand of desensitizing toothpaste, Colgate Sensitive Pro Relief Repair and Prevent, Colgate Sensitive Pro Relief Enamel Repair, Colgate Sensitive Pro Relief Multi Protection. Hines D, Rinaudi L, Xu S, Lavender S, Pilch S: The Use of Confocal Laser Scanning Microscopy and a Novel Imaging Program for Quantifying Dentine Tubule Occlusion. Sriranganathan D, Chen X, Hing KA, Kanwal N, Hill RG. Colgate SENSITIVE INSTANT Relief tannkrem med Pro-Argin teknologi gir umiddelbar* og langvarig smertelindring av ising i tennene. Therefore, it was considered to be rejected at a p valueof 0.05. These toothpaste Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. Colgate Sensitive Pro-Relief Instant Relief Sensitive Toothpaste - 75ml More Images Colgate Sensitive Pro-Relief Instant Relief works as a shield that blocks pathways to pain instantly. Participants were recalled at interim efficacy intervals of three days, two weeks, four weeks, and six weeks for assessment of sustained relief. J Oral Sci. Mintsmak. https://doi.org/10.17352/2394-8418.00003. This clinical trial has not included a run-in or washout period before the test phase due to time constraints and compliance of the potential participants. Formulated with Pro-Argin technology, Colgate Sensitive Pro-Relief is clinically proven instant and lasting sensitivity relief*. After six weeks, FCPS-based dentifrices showed greater clinical efficacy with mean scores (1.801.73) than other treatment arms for waterjet stimulated DH. Lg i kurv. BMC Oral Health Hu et al. Statistical Package for the Social Sciences software v.21.0. 2009;20 (Spec Iss):123130. The Gum Health Physical is a new interactive digital tool you can use to quickly evaluate your patients in-office, and give them a personalized report they can use at home. Colgate-Palmolive Company 2018. Comparing the efficacy in reducing dentin hypersensitivity of a new toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride to a commercial sensitive toothpaste containing 2% potassium ion: an eight-week clinical study on Canadian adults. However, Pro-argin formulation showed 8% more improvement in clinical symptoms of DH than strontium acetate formulation one minute after application. In this way, variability in individuals' pain response was tried to be controlled and will be discussed in part 2 of this manuscript. For instant relief, just apply directly to the sensitive tooth with fingertip and gently massage for one minute. Children 6 years and younger: use a pea-sized amount for supervised tooth brushing to minimise swallowing. For best performance, keep cap closed when not in use. Grnberg C, Bauer F, Crispin A, Jakob M, Hickel R, Draenert ME. who examined FCPS and Pro-argin formulations in 2018. The participants with self-reported sensitivity in teeth were clinically diagnosed with DH. Pro-Argin showed a greater reduction in DH with mean scores of (1.340.68) (4.201.70) (3.052.17) followed by strontium acetate (1.570.81) (4.651.87) (3.751.97) on SCASS and VAS for mechanical and water jet stimuli, one minute after application. reporting the instant relief from DH by 44.1% with Pro-argin on SCASS. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. in 2019 using BioMin F and Pro-argin. 2. This study investigated the relief from pain in DH in one minute after applying over the counter (OTC) dentifrices with Pro-Argin and strontium acetate and directly compared them with fluoro-calcium phospho-silicate (FCPS)-based dentifrices for immediate and sustained inhibition of painful stimulus provoking DH. Product Details Characteristics and Benefits Characteristics: Unique Pro-Argin TM/MC technology based on natural process of tubule occlusion Schulz KF, Altman DG, Moher D. CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials. SEALS & REPAIRS: Pro-Argin technology helps to seal and repair the sensitive areas of teeth. J Clin Dent 20 (2009), special issue 17-22, 3. Dentine hypersensitivity. Oral dentifrices have been marketed extensively for pain relief in one minute after topical application on sensitive teeth, with the claims of several dentists recommending the formulations containing Pro-argin and 8% strontium acetate. Samueli A, Hill R, Gillam D. Bioactive glasses in the management of dentine hypersensitivity: a review. Participants were randomly allocated to four treatment arms and randomly assigned with OTC dentifrices having FCPS, Pro-argin, strontium acetate, and sodium fluoride (NaF) with an allocation ratio of 1:1:1:1. Helps repair teeth by forming a mineral layer that re-constructs the sensitive part of the tooth, with regular use; Seals the open nerve channels for instant relief, and helps prevent sensitivity from re-occurring; Plus the freshness you trust from Colgate It has stannous fluoride as an active ingredient. Another study by Vu Pham and Anh Nguyen reported clinical improvement in DH by 38.9% on SCASS and 40.2% on VAS for mechanical stimulated DH immediately after application of Pro-argin [25]. The first post-treatment measure of SCASS and VAS scores was obtained immediately after removing dentifrices from teeth. 90 sold. FCPS was incorporated in OTC dentifrice with calcium, low contents of fluoride, and high contents of phosphate ions. The total sample size was 140 participants, with thirty-five in each group. Instant relief when applied directly to the sensitive tooth with the fingertip and gently massaged for 1 minute. Colgate Sensitive Instant Relief Multiprotection Toothpaste gives you clinically proven lasting relief from sensitivity for 8 weeks when you use it twice a day. SA was the principal investigator and has contributed to design, data acquisition, analysis, and interpretation, and drafted the manuscript. It effectively occludes open dentine tubuli instantly* and builds a strong calcium-rich layer that ensures long-lasting relief from the pain of sensitivity.1,2 The protective layer remains strong even after exposure to acid attacks.3, of respondents confirmed reduced dentine hypersensitivity with Colgate SENSITIVE INSTANT Relief Repair & Prevent toothpaste6,, of respondents were happy with their dentists recommending Colgate SENSITIVE INSTANT Relief Repair & Prevent toothpaste6,, of respondents noticed long-lasting and instant* relief when brushing with Colgate SENSITIVE INSTANT Relief toothpaste7,, Colgate SENSITIVE PRO-Relief has been rebranded to Colgate SENSITIVE INSTANT Relief. They explored greater tubular occlusion potential and more acid resistance of Pro-argin in comparison to FCPS after subsequent seven days of application on dentinal discs [38]. While your patients may have dentine hypersensitivity in common, their oral care needs will vary. Panagakos F, Schiff T, Guignon A. Dentin hypersensitivity: effective treatment with an in-office desensitizing paste containing 8% arginine and calcium carbonate. Innehller slipmedel med ltt polerande effekt p flckar samt fluor som minskar risken fr karies. 2009;20(1):106. 2015;28(1):404. Naturally, the researchers wondered whether it could help shield a person from acquiring the virus. Colgate-Palmolive Company 2018. Bae J-H, Kim Y-K, Myung S-K. Desensitizing toothpaste versus placebo for dentin hypersensitivity: a systematic review and meta-analysis. It was measured by assaying change in SCASS scores of pains with Pro-argin and 8% strontium acetate after one minute of topical application on the sensitive teeth. Anyone you share the following link with will be able to read this content: Sorry, a shareable link is not currently available for this article. Klubpris: 25,46 kr. Pro-Argin technology helps to seal and repair . Colgate SENSITIVE INSTANT Relief Repair & Prevent toothpaste provides instant* and long-lasting sensitivity relief and lasting gum protection: PRO-ARGIN Technology repairs sensitive areas of the teeth for instant and long-lasting pain relief1,2, Zinc helps to strengthen gums and to prevent recession a key cause of sensitivity3. 75 ml. Customers also search toothpaste colgate sensitive colgate enamel colgate pro relief colgate pain relief Buy Colgate Sensitive Pro Relief and get the best deals at the lowest prices on eBay! Google Scholar. 29,95 kr. 0:00 / 0:30 Colgate Sensitive Pro-Relief Challenge Advert April 2012 178,990 views Mar 29, 2012 Take the Colgate Sensitive Pro-Relief Challenge to Show more 15 Dislike Share. SHOULD A PATIENT CONTINUE USING Colgate SENSITIVE INSTANT Relief Repair & Prevent TOOTHPASTE ONCE THE DENTINE SENSITIVITY HAS GONE? The sealed envelope contained details of unique subject numbers assigned individually in ascending order, group titles, and treatment codes and was placed in the box. The current study outcomes showed significant decrease in pain scores of air-blasts and water jet stimulated DH with FCPS based dentifrices compared to Pro-argin and 8% strontium acetate after two, four, and six weeks subsequently, as depicted in Tables 4 and 5. Colgate SENSITIVE Instant(Pro) Relief Enamel Repair Toothpaste 75ml (Pck 4,6,12) 15.99 to 39.99. compared the Pro-Argin formulation with a calcium sodium phosphosilicate toothpaste, demonstrating 88% versus 50% occlusion respectively. Gently and effectively removes stains. 0. Hence, the effectiveness of clinically available formulations of FCPS in OTC dentifrices needs further exploration for the permanent management of DH. The maximum sampling time was 15min. The study's primary objective was to investigate pain relief in one minute after topical application of Pro-argin and strontium acetate on sensitive teeth in DH. Colgate Sensitive Pro-Relief efektywnie i szybko znosi nadwraliwo zbw, zamyka kanaliki zbinowe w ktrych s zakoczenia nerww, dziki czemu blokuje bl. All rights reserved. BMC Oral Health 21, 498 (2021). Last updated on May 11, 2021. After six weeks, Pro-argin-based dentifrices showed greater clinical efficacy with mean scores (2.151.92) than other treatment arms for mechanical stimulated DH. These findings were similar to a previous study conducted by Schiff et al. All rights reserved. Baseline scores were recorded to measure the intensity of pain due to DH on SCASS with scores2 [22] against air blast stimulus with a triple syringe of the dental unit and on a linear VAS of 10cm length with scores4cm [23], against mechanical stimulus with a dental probe and water jet stimulus with a triple syringe. Frequency of dentin hypersensitivity: a cross-sectional study. Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste contains Sodium Fluoride (1450ppmF) the recommended fluoride level for effective caries prevention.4. observed a significantly greater reduction in sensitivity from air and tactile stimuli when compared to a potassium ion toothpaste, an effect sustained at two, four and eight weeks of use. A meta-analysis by Grnberg et al. Int J Dent. Colgate Sensitive Pro-Relief toothpastes have been formulated to provide instant and lasting relief from the pain associated with sensitive teeth. Was this answer helpful? * For instant relief, apply directly to the sensitive tooth with finger tip and gently massage for 1 minute. Compend Contin Educ Dent. Colgate uses need to categorize. See patient relevant information on Colgate.com. 1997;24(11):80813. A randomised controlled, triple-blinded, phase-3 clinical trial was conducted at the Department of Periodontology at Dr Ishrat-ul-Ebad Khan Institute of Oral Health Sciences (DIKIOHS) in Dow University of Health Sciences (DUHS), Karachi, Pakistan from September 2019 to December 2020. Kp nu. The sensitive toothpaste works in different ways to fight cavities, remove plaque, promote gum health and freshen breath. Written consent was obtained from all participants to participate in the six-week clinical trial. These outcomes were found in concordance with the previous controlled clinical trial conducted by Patel et al. PubMed Central https://doi.org/10.1186/s12903-021-01864-x, DOI: https://doi.org/10.1186/s12903-021-01864-x. statement and There was statistically no significant difference in the baseline characteristics of gender, age, baseline mean scores of clinical parameters of SCASS, and VAS used for mechanical and water jet stimuli between the four treatment groups (p>0.05). All rights reserved. I want to acknowledge the administrative faculty and staff assistants in the Department of Periodontology for facilitation in data collection. Innehll Colgate Sensitive Instant Relief Enamel Repair r en fluortandkrm med Pro-Argin-teknologi som ger omedelbar smrtlindring vid ilningar i tnderna. Dentin hypersensitivity is characterized by a short, sharp pain arising from open dentin tubules in exposed dentin in response to external stimuli, which cannot be attributed to any other defect or disease. J Dent Probl Solut. Colgate SENSITIVE INSTANT Relief Repair & Prevent toothpaste with PRO-ARGIN Technology and Zinc provides clinically proven instant* and lasting sensitivity relief1-2 plus lasting gum protection3. The prevalence of DH was found to vary from about 5 to 62% owing to the use of different diagnostic and measuring tools and age groups in the published literature, with the best average estimate of 34% worldwide [3]. Internal report 2018, 5. Colgate Sensitive Pro-relief Instant Relief. Layer T, Hughes N. Evidence for the efficacy of an 8% strontium acetate dentifrice for instant and lasting relief of dentin hypersensitivity. Plus it has the freshness you trust from Colgate! Individuals either with dental caries, heavily restored, or cracked teeth, or with orthodontic or prosthetic appliances, or with localised or generalised gingivitis or pulpitis and heavy calculus or using any desensitising toothpaste or mouth wash or any other desensitising products up to six weeks before the study were excluded from this trial. Shrimathi S. Effect of BiominF, NovaminR, Argin and nanohydroxy particles containing dentifrices on dentine hypersensitivity and gingivitis among 3544 years aged population of Madurai district: a randomized controlled trial (RCT). In addition, the frequency of participants diagnosed with DH using air blast stimulus was observed as 36.8% at the time of enrolment in the six-week clinical trial that was found consistent with findings of a survey report demonstrating 36.4% frequency of DH among adults in Karachi, Pakistan [24]. Gillam D, Talioti E. The Management of Dentine Hypersensitivity. Manage cookies/Do not sell my data we use in the preference centre. Width 17 Height 5 Depth 3.8 Show More Payment & Refunds Vu Pham T, Anh Nguyen T. Clinical evaluation of the desensitizing efficacy of a paste containing 8% arginine and calcium carbonate. [33] again reported a 54% clinical reduction in DH with Pro-argin in eight weeks clinical trial using SCASS. According to Holland's guidelines of conducting a trial for managing DH, two diagnostic tools are sufficient for quantitative assessment of the clinical efficacy of desensitisers. 2018. Book Paired sample T-test was used to compute mean scores to observe change relative to baseline at each time point. Am J Dent. Results of our study, together with the results of the previous studies, confirm the immediate clinical efficacy of Pro-argin for the relief of DH. Comparative evaluation of the efficacy of three commercially available toothpastes on dentin hypersensitivity reduction: an 8-week clinical study. Dent Health Curr Res. If the enamel is too thin, has tiny tubules that reveal the underlying dentin, or is worn down in some places. Clinically proven amino acid formula with Pro-Argin technology to provide sensitivity relief. 2017;2017:2. Desensitizing toothpastes depolarize the nerves to reduce pain signals to the brain, while occlusives block the dentin tubules to prevent painful stimuli affecting dentinal fluids.

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